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Plasmid Core

Overview of Services

The Plasmid Production Core is a full service facility assisting with the design and cloning of AAV expression cassettes to large scale production of research grade plasmids. The design and cloning of AAV expression cassettes will allow for optimum levels of expression, while the large scale production of research grade plasmid is for the use in preclinical as well as IND enabling toxicology grade and GMP production. The core supports the production of plasmid DNA at a variety of scales ranging from small scale (100mgs) to large scale productions (500mg), all manufactured with single-use, disposable materials. All DNA plasmids will have passed rigorous quality control standards.

Leadership

 

Kristin Heller, PhD, Supervisor
614-355-3660
kristin.heller@nationwidechildrens.org

 

Andrew Moreo, Manager
614-355-3464
Andrew.moreo@nationwidechildrens.org

 

Location and hours of operation

Hours   Location

8AM-5PM, Monday-Friday

  The Research Institute at Nationwide Children's Hospital
  700 Children's Dr
  Columbus, OH, 43205

Links and Resources

Contacts

Name Role Phone Email Location
GMPPlasmidCore@nationwidechildrens.org

 

 
GMPPlasmidCore@nationwidechildrens.org
 

 

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