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Biologics Manufacturing Resource

Overview of Services

The Biologics Manufacturing Resource (BMR) comprises over 2300 sq ft of laboratory suites, including ISO 7 cleanrooms, a QC laboratory, research and development, LN2 storage, inventory, and associated offices. Critical spaces maintain controlled access using an electronic card key system. Current Good Manufacturing Practices (cGMPs) are followed for all BMR products. A robust quality assurance program is in place that includes environmental monitoring, continuous equipment and facility monitoring with remote alarms, appropriate gowning practices, and documented facility and equipment cleaning and maintenance.  



The BMR maintains these facilities, equipment, and personnel for manufacturing a wide range of cellular therapeutic products for clinical trials, such as NK cells, CAR T cells, and CARNK Cells. Biologics Manufacturing also manufactures irradiated CSTX002 feeder cells for ex vivo expansion of NK cells, available at clinical grade or research grade for process development or preclinical validation. Along with all the cell products manufactured by the BMR, Biologics Manufacturing completes the processing of a tissue engineered vascular graft (TEVG) in support of an ongoing clinical trial. Additional products can be offered through process development or technology transfer as needed. 


Lawrence Gazda, Director


Prithy Martis, Supervisor


Shane Wellman, Business Manager


Location and hours of operation

Hours   Location

8AM-5PM, Monday-Friday

  The Research Institute at Nationwide Children's Hospital
  700 Children's Dr
  Columbus, OH, 43205

Links and Resources


Name Role Phone Email Location
Prithy Martis
Shane Wellman
Business Manager
Lawrence Gazda
Research IV