Viral Vector Core

About Our Core

The Viral Vector Core supplies recombinant adeno-associated virus (rAAV) vectors of superior quality to individual research laboratories. The Core is a full-service facility assisting with the design of AAV expression cassettes for optimum levels of gene expression in target tissues that enable investigators to transition seamlessly from the bench to the bedside.

The core now supports production of eight different recombinant AAV vector serotypes (AAV1, AAV2, AAV2NHB (non-heparin binding), AAV5, AAV6, AAV8, AAV9 & AAVrh74) at a variety of scales ranging from small (2E+12VPs) to custom large-scale productions (>1E+14VPs) to support large animal and preclinical toxicology studies. All research grade vectors are purified to remove empty particles and have passed rigorous quality control standards.

Leadership

Andy Moreo

Andrew.Moreo@nationwidechildrens.org | (614) 355-3464

Location and hours of operation

Links and Resources

1. Viral Vector Core at The Research Institute at Nationwide Children's Hospital