Transgenic and Embryonic Stem Cell Core Lab


Overview of Services


The Transgenic and Embryonic Stem Cell Core is devoted to assisting investigators with all aspects of mouse embryo manipulation, including the design, creation and rederivation of genetically engineered mice.

 

Leadership


K. John McLaughlin, Ph.D. | Director

 

Services and Pricing

 

* Animal housing and breeding management costs will be charged subsequent to one week post-weaning at a cost of $1 per cage/per day. 

 

* Prices do not include cost of mice that will be needed for experiments.  Final cost will depend on number of mice ordered for your project.

 

Import/Export Handling Fee:  Basic cost for transportation of embryos.  Actual transportation cost will depend on destination or source location.

 

CATEGORY

SERVICE

 2015 PRICE

 TRINCH

 CCC/OSU

 Academic

 List

Cryopreservation

Embryo Freezing & Storage for 3 yrs

 $           1,100.00

 $    1,300.00

 $    1,300.00

 $    1,300.00

 

Sperm Cryopreservation (JAX kit) three strains

 $           3,800.00

 $    3,900.00

 $    3,900.00

 $    3,900.00

 

Sperm Cryopreservation (JAX kit) one strain

 $           1,400.00

 $    1,500.00

 $    1,500.00

 $    1,500.00

 

Sperm Cryopreservation TRINCH for 3 years

 $              850.00

 included

 included

 included

 

Extended Cryopreservation Storage - additional 1 year for up to 10 samples/vials/straws (after 3 year storage period expires)

 $              100.00

 $       100.00

 $       100.00

 $       100.00

 

 

 

 

 

 

ES Chimera Generation

Blastocyst Injection

 $           3,500.00

 $    4,100.00

 $    4,100.00

 $    4,100.00

 

Morula Aggregation

 $           3,200.00

 $    3,800.00

 $    3,800.00

 $    3,800.00

 

C57Bl6 (KOMP) ES Cell Blastocyst Injection

 $           4,500.00

 $    5,000.00

 $    5,000.00

 $    5,000.00

Pronuclear Injection

CBAxC57F1, FVB, C3HxC57F1

 $           3,000.00

 $    3,500.00

 $    3,500.00

 $    3,500.00

 

                            C57Bl/6J

 $           5,500.00

 $    6,000.00

 $    6,000.00

 $    6,000.00

Zygote injection

CRISPR/Cas9 cytoplasm or pronuclear

 $           3,000.00

 $    3,500.00

 $    3,500.00

 $    3,500.00

IVF

In-vitro Fertilization

 $           1,700.00

 $    1,800.00

 $    1,800.00

 $    1,800.00

 

 

 

 

 

 

Additional Services

Cre or FLP Electroporation

 $           1,700.00

 $    2,000.00

 $    2,000.00

 $    2,000.00

 

Embryonic Stem Cell Line Rederivation

 $           3,200.00

 $    3,500.00

 $    3,500.00

 $    3,500.00

 

ES Cell Targeting

 $           3,600.00

 $    4,600.00

 $    4,600.00

 $    4,600.00

 

ES Cell Screening

 $           3,500.00

 $    4,500.00

 $    4,500.00

 $    4,500.00

 

Speed Backcrossing (Congenics) (approx. 15 months)

 $           8,000.00

 $ 10,000.00

 $ 10,000.00

 $ 10,000.00

 

High Speed Backcrossing (Congenics) (approx. 9 months)

 $        12,000.00

 $ 15,000.00

 $ 15,000.00

 $ 15,000.00

 

Rederivation by Embryo Transfer

 $              800.00

 $    1,100.00

 $    1,100.00

 $    1,100.00

 

Surplus C57Bl/6J males, 3-6 weeks old

 $                   2.00

 n/a

 n/a

 n/a

 

Long Term Animal Housing (per day/per cage)

 $                   1.00

 $            1.00

 $            1.00

 $            1.00

 

Import/Export Handling Fee

 $           1,000.00

 $    1,000.00

 $    1,000.00

 $    1,000.00

 

 

 

 

 

 

Project design

CRISPR/Cas9 design, synthesis, injection & genotype

 contact core

 

 

 

 

knockout/knockin via ES cell homologous recombination

 contact core

 

 

 

Training

Training (Per week)

 $           2,000.00

 $    2,500.00

 $    2,500.00

 $    2,500.00

 

 

 

 

 

 

           
           

ADDITIONAL NOTATIONS FOR WEBPAGE:

       

1.  This applies to all services, so statement to be clearly visible on main page below services:
Prices do not include cost of mice that will be needed for experiments.  Final cost will depend on number of mice ordered for your project.

           

2.  Statement to be included in description for Import/Export Handling Fee:
Basic cost for transportation of embryos.  Actual transportation cost will depend on destination or source location.

 

 Location 700 Children's Drive, W411, Columbus, OH 43205

 

Links and Resources 

1. http://transgenicmousecore.nchresearch.org